A Study on Antibacterial, Antioxidant, and Hepatoprotective Efficacy of Elephantopus scaber L.
نویسندگان
چکیده
Elephantopus scaber is an herb widely used in folk remedies Vietnam, especially the treatment of liver disease. However, scientific studies evaluating activity and ability to treat disease a way are still very limited. This study evaluated antibacterial, antioxidant, acute toxicity hepatoprotective efficacy E. extracts. The extracts restricted growth 6 types bacteria, being particularly most effective against coli. It was found that leaves extract more efficient than root, stem, flower, whole plant DPPH assay showed flower had highest antioxidant (EC50 = 60.29 µg/mL). (>5000 mg/kg) also did not cause mice. Additionally, effectively protected recovered mice cells damaged by CCl4. reduction enzyme levels (AST ALT) similar between silymarin. efficiency illustrated morphology histology cells. healed recovering cell diameter, reducing inflammation swelling increasing Hb concentration.
منابع مشابه
ANTIBACTERIAL STUDIES ON LEAF EXTRACT OF ELEPHANTOPUS SCABER Linn
Methanolic extract of Elephantopus scaber Linn was investigated for its antibacterial activity against Staphylococcus aureus (NCIM - 2079), Escherichia coli (NCIM-2067), Bacillus subtilis (NCIM-2063), Pseudomonas aeruginosa (NCIM-2036), Proteus vulgaris (NCIM-2027) at 100 μg/disc by using disc diffusion method. The extract showed significant anti bacterial activity and were compared to chloramp...
متن کاملHepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice
Elephantopus scaber has been traditionally used as liver tonic. However, the protective effect of E. scaber on ethanol-induced liver damage is still unclear. In this study, we have compared the in vivo hepatoprotective effect of E. scaber with Phyllanthus niruri on the ethanol-induced liver damage in mice. The total phenolic and total flavanoid content of E. scaber ethanol extract were determin...
متن کاملA Novel Terpenoid from Elephantopus Scaber – Antibacterial Activity on Staphylococcus Aureus: A Substantiate Computational Approach
Staphylococcus aureus has gained much attention in the last decade as it is a major cause of the Urinary Tract Infection in Diabetic patients. The Extended Spectrum β-Lactamases (ESβL) producers are highly resistant to several conventional antibiotics. This limits the therapeutic options.Hence efforts are now taken to screen few medicinal plants, which are both economic and less toxic. Among th...
متن کاملSesquiterpene lactones from Elephantopus scaber
The ethanolic and acetone extracts of the whole plant of Elephantopus scaber were found to contain ethyl hexadecanoate, ethyl-9,12-octadecadienoate, ethyl-(Z)9-octadecenoate, ethyl octadecanoate, lupeol, stigmasterol, stigmasterol glucoside, deoxyelephantopin (1) and two new germacranolide sesquiterpene lactones named 17,19-dihydrodeoxyelephantopin (2) and iso-17,19-dihydrodeoxyelephantopin (3)...
متن کاملAntioxidant and Wound Healing Activity of Polyherbal Fractions of Clinacanthus nutans and Elephantopus scaber
Elephantopus scaber and Clinacanthus nutans are traditionally used as wound healing herb. The objective of the present study is to develop a new polyherbal formulation, by comparison, the herbal combination of Elephantopus scaber and Clinacanthus nutans as an in vitro antioxidant activity with their individual herbal activity followed by fractionation of polyherbal formulation for in vivo wound...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Sains Malaysiana
سال: 2022
ISSN: ['0126-6039', '2735-0118']
DOI: https://doi.org/10.17576/jsm-2022-5112-13